Chemistry:Fructose 6-phosphate
| |
| |
| Names | |
|---|---|
| IUPAC name
6-O-Phosphono-α-D-fructofuranose
| |
| Other names
β-D-fructose 6-phosphate,
fructose 6-phosphate | |
| Identifiers | |
3D model (JSmol)
|
|
| Abbreviations | F6P |
| ChEBI | |
| ChemSpider | |
| KEGG | |
PubChem CID
|
|
| UNII | |
| |
| |
| Properties | |
| C6H13O9P | |
| Molar mass | 260.14 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
| |
| Infobox references | |
Fructose 6-phosphate (sometimes called the Neuberg ester) is a derivative of fructose, which has been phosphorylated at the 6-hydroxy group. It is one of several possible fructosephosphates. The β-D-form of this compound is very common in cells.[1][2] The great majority of glucose is converted to fructose 6-phosphate upon entering a cell. Fructose is predominantly converted to fructose 1-phosphate by fructokinase following cellular import.
History
The name Neuberg ester comes from the German biochemist Carl Neuberg. In 1918, he found that the compound (later identified as fructose 6-phosphate) was produced by mild acid hydrolysis of fructose 2,6-bisphosphate.[3]
In glycolysis
Fructose 6-phosphate lies within the glycolysis metabolic pathway and is produced by isomerisation of glucose 6-phosphate. It is in turn further phosphorylated to fructose-1,6-bisphosphate.
| α-D-glucose 6-phosphate | Phosphoglucose isomerase | α-D-fructose 6-phosphate | Phosphofructokinase-1 | α-D-fructose 1,6-bisphosphate | ||
| image:alpha-D-glucose-6-phosphate wpmp.png | image:beta-D-fructose-6-phosphate wpmp.png | image:beta-D-fructose-1,6-bisphosphate wpmp.png | ||||
| ATP | ADP | |||||
| 75px | 75px | |||||
| Pi | H2O | |||||
| Phosphoglucose isomerase | Fructose bisphosphatase | |||||
Compound C00668 at KEGG Pathway Database. Enzyme 5.3.1.9 at KEGG Pathway Database. Compound C05345 at KEGG Pathway Database. Enzyme 2.7.1.11 at KEGG Pathway Database. Enzyme 3.1.3.11 at KEGG Pathway Database. Reaction [1] at KEGG Pathway Database. Compound C05378 at KEGG Pathway Database.
See also
References
- ↑ Berg, Jeremy M.; Tymoczko, Stryer (2002). Biochemistry (5th ed.). New York: W.H. Freeman and Company. ISBN 0-7167-3051-0. https://archive.org/details/biochemistrychap00jere.
- ↑ Nelson, D. L.; Cox, M. M. "Lehninger, Principles of Biochemistry" 3rd Ed. Worth Publishing: New York, 2000. ISBN:1-57259-153-6.
- ↑ Fruton, Joseph S. Proteins, Enzymes, Genes: The Interplay of Chemistry and Biology. Yale University Press: New Haven, 1999. p 292
 |  |
