Chemistry:Thiouric acid

Thiouric acid
Names
	IUPAC name 6-Thioxo-7,9-dihydro-1H-purine-2,8(3H,6H)-dione
	Other names 6-Thiouric acid
Identifiers
CAS Number	2002-60-0 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:80608;
ChemSpider	2297400;
KEGG	C16613;
PubChem CID	3032417;
UNII	7F23ZQP3EM ;
	InChI InChI=1S/C5H4N4O2S/c10-4-6-1-2(7-4)8-5(11)9-3(1)12/h(H4,6,7,8,9,10,11,12) Key: SXHQUGJSTGOXMD-UHFFFAOYSA-N;
	SMILES c12c([nH]c(=O)[nH]1)[nH]c(=O)[nH]c2=S;
Properties
Chemical formula	C5H4N4O2S
Molar mass	184.17 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Thiouric acid, more accurately called 6-thiouric acid, is a main inactive metabolite of the immunosuppressive drugs azathioprine, mercaptopurine and tioguanine.^[1]^[2]

References

↑ Mutschler, Ernst; Schäfer-Korting, Monika (2001) (in de). Arzneimittelwirkungen (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 107, 936. ISBN 3-8047-1763-2.
↑ Ansari, A; Aslam, Z; De Sica, A; Smith, M; Gilshenan, K; Fairbanks, L; Marinaki, A; Sanderson, J et al. (2008). "Influence of xanthine oxidase on thiopurine metabolism in Crohn's disease". Alimentary Pharmacology & Therapeutics 28 (6): 749–57. doi:10.1111/j.1365-2036.2008.03768.x. PMID 18557988.

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