Chemistry:Thiouric acid
From HandWiki
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| Names | |
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| IUPAC name
6-Thioxo-7,9-dihydro-1H-purine-2,8(3H,6H)-dione
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| Other names
6-Thiouric acid
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| Identifiers | |
3D model (JSmol)
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| KEGG | |
PubChem CID
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| Properties | |
| C5H4N4O2S | |
| Molar mass | 184.17 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Thiouric acid, more accurately called 6-thiouric acid, is a main inactive metabolite of the immunosuppressive drugs azathioprine, mercaptopurine and tioguanine.[1][2]
References
- ↑ Mutschler, Ernst; Schäfer-Korting, Monika (2001) (in de). Arzneimittelwirkungen (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 107, 936. ISBN 3-8047-1763-2.
- ↑ Ansari, A; Aslam, Z; De Sica, A; Smith, M; Gilshenan, K; Fairbanks, L; Marinaki, A; Sanderson, J et al. (2008). "Influence of xanthine oxidase on thiopurine metabolism in Crohn's disease". Alimentary Pharmacology & Therapeutics 28 (6): 749–57. doi:10.1111/j.1365-2036.2008.03768.x. PMID 18557988.
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