Chemistry:Argopsin
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Short description: Chemical compound
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IUPAC name
2,8-Dichloro-9-hydroxy-3-methoxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-10-carbaldehyde
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Other names
1-Chloropannarin
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3D model (JSmol)
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PubChem CID
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Properties | |
C18H14Cl2O6 | |
Molar mass | 397.20 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Tracking categories (test):
Argopsin, also known as 1-chloropannarin, is a secondary metabolite produced by many lichen species, such as Biatora cuprea[1] and Micarea lignaria.[2] Argopsin was first isolated from the lichen Argopsis friesiana.[3] The chemical composition of argopsin is 2,7-Dichloro-3-hydroxy-8-methoxy-1,6,9-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-4-carbaldehyde.
Uses
Argopsin can have photohemolytic effect when activated under ultraviolet light with a wavelength of 366 nm.[4]
Argopsin has been shown to have in vitro effect on Leishmania at a concentration of 50 µg/ml.[5]
References
- ↑ Hörður Kristinsson (2016). Íslenskar fléttur. Reykjavík: Hið íslenska bókmenntafélag. ISBN 978-9979-66-347-8
- ↑ Flóra Íslands. Viðarkúpa - Micarea lignaria. Sótt 4. mars 2017.
- ↑ Huneck, Siegfried; Lamb, I.Mackenzee (1975). "1′-Chloropannarin, a new depsidone from Argopsis friesiana: Notes on the structure of pannarin and on the chemistry of the lichen genus Argopsis". Phytochemistry 14 (7): 1625–1628. doi:10.1016/0031-9422(75)85363-5.
- ↑ Hidalgo, M. E.; Fernández, E.; Quilhot, W.; Lissi, E. A. (1993). "Photohemolytic activity of lichen metabolites". Journal of Photochemistry and Photobiology. B, Biology 21 (1): 37–40. doi:10.1016/1011-1344(93)80161-2. PMID 8289110.
- ↑ Fournet, Alain; Ferreira, Maria-Elena; De Arias, Antonieta Rojas; De Ortiz, Susana Torres; Inchausti, Alba; Yalaff, Gloria; Quilhot, Wanda; Fernandez, Ernesto et al. (1997). "Activity of Compounds Isolated from Chilean Lichens Against Experimental Cutaneous Leishmaniasis". Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 116 (1): 51–54. doi:10.1016/S0742-8413(96)00127-2. PMID 9080673.
Original source: https://en.wikipedia.org/wiki/Argopsin.
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