Biology:STK19
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Serine/threonine-protein kinase 19 is an enzyme that in humans is encoded by the STK19 gene.[1][2][3]
This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants.[3]
See also
References
- ↑ "Characterisation of the novel gene G11 lying adjacent to the complement C4A gene in the human major histocompatibility complex". Hum Mol Genet 3 (3): 481–8. Jul 1994. doi:10.1093/hmg/3.3.481. PMID 8012361.
- ↑ "The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase". J Biol Chem 273 (47): 30954–60. Dec 1998. doi:10.1074/jbc.273.47.30954. PMID 9812991.
- ↑ 3.0 3.1 "Entrez Gene: STK19 serine/threonine kinase 19". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8859.
Further reading
- Yu CY (1991). "The complete exon-intron structure of a human complement component C4A gene. DNA sequences, polymorphism, and linkage to the 21-hydroxylase gene.". J. Immunol. 146 (3): 1057–66. doi:10.4049/jimmunol.146.3.1057. PMID 1988494.
- "Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region. Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication.". J. Biol. Chem. 269 (11): 8466–76. 1994. doi:10.1016/S0021-9258(17)37217-4. PMID 8132574.
- "Complete sequence of the complement C4 gene from the HLA-A1, B8, C4AQ0, C4B1, DR3 haplotype.". Immunogenetics 43 (4): 250–2. 1996. doi:10.1007/s002510050059. PMID 8575831.
- "Four ubiquitously expressed genes, RD (D6S45)-SKI2W (SKIV2L)-DOM3Z-RP1 (D6S60E), are present between complement component genes factor B and C4 in the class III region of the HLA.". Genomics 53 (3): 338–47. 1998. doi:10.1006/geno.1998.5499. PMID 9799600.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. 2003. doi:10.1038/nature02055. PMID 14574404. Bibcode: 2003Natur.425..805M.
- "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.". Genome Res. 13 (12): 2621–36. 2004. doi:10.1101/gr.1736803. PMID 14656967.
- "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.". Genomics 83 (1): 153–67. 2004. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
- "Characterization of Hap/BAG-1 variants as RP1 binding proteins with antiapoptotic activity.". Int. J. Cancer 117 (6): 896–904. 2005. doi:10.1002/ijc.21259. PMID 15986447.
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