Biology:CPNE6
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Copine-6 is a protein that in humans is encoded by the CPNE6 gene.[1][2]
This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.[2]
References
- ↑ "N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression". FEBS Lett 428 (1–2): 80–4. Jul 1998. doi:10.1016/S0014-5793(98)00497-9. PMID 9645480.
- ↑ 2.0 2.1 "Entrez Gene: CPNE6 copine VI (neuronal)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9362.
External links
- Human CPNE6 genome location and CPNE6 gene details page in the UCSC Genome Browser.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Localization and subcellular distribution of N-copine in mouse brain". J. Neurochem. 72 (1): 373–9. 1999. doi:10.1046/j.1471-4159.1999.0720373.x. PMID 9886090.
- "Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified in osteosarcoma". FEBS Lett. 453 (1–2): 77–80. 1999. doi:10.1016/S0014-5793(99)00700-0. PMID 10403379.
- "Characterization of human copine III as a phosphoprotein with associated kinase activity". Biochemistry 39 (42): 13034–43. 2000. doi:10.1021/bi001250v. PMID 11041869.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
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