Biology:Protein-serine epimerase
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protein-serine epimerase | |||||||||
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Identifiers | |||||||||
EC number | 5.1.1.16 | ||||||||
CAS number | 169592-52-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a protein-serine epimerase (EC 5.1.1.16) is an enzyme that catalyzes the chemical reaction
- [protein]-L-serine [math]\displaystyle{ \rightleftharpoons }[/math] [protein]-D-serine
Hence, this enzyme has one substrate, [protein]-L-serine, and one product, [protein]-D-serine.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is [protein]-serine epimerase. This enzyme is also called protein-serine racemase.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1WTC.
References
- "Isolation and characterization of a peptide isomerase from funnel web spider venom". J. Biol. Chem. 270 (28): 16719–23. 1995. doi:10.1074/jbc.270.28.16719. PMID 7622482.
Original source: https://en.wikipedia.org/wiki/Protein-serine epimerase.
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