Chemistry:3-Bromomethylphenidate

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Short description: Chemical compound
3-Bromomethylphenidate
3-Bromomethylphenidate.svg
Identifiers
PubChem CID
ChemSpider
Chemical and physical data
FormulaC14H18BrNO2
Molar mass312.207 g·mol−1
3D model (JSmol)

3-Bromomethylphenidate (3-Br-MPH) is a compound from the phenidate family, which has reportedly been sold as a designer drug. It showed the most potent binding to the dopamine transporter of a series of ring-substituted methylphenidate derivatives, and produced stimulant effects in animal studies.[1][2][3]

See also

References

  1. "Binding of bromine-substituted analogs of methylphenidate to monoamine transporters". European Journal of Pharmacology 264 (2): 177–82. October 1994. doi:10.1016/0014-2999(94)00460-9. PMID 7851480. 
  2. "Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs". Journal of Medicinal Chemistry 39 (6): 1201–9. March 1996. doi:10.1021/jm950697c. PMID 8632426. 
  3. "Quantitative structure-activity relationship studies of threo-methylphenidate analogs". Bioorganic & Medicinal Chemistry 18 (20): 7221–38. October 2010. doi:10.1016/j.bmc.2010.08.034. PMID 20846865.