Biology:L-ascorbate—cytochrome-b5 reductase

From HandWiki
Revision as of 19:55, 14 October 2021 by imported>Scavis2 (linkage)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
L-ascorbate—cytochrome-b5 reductase
Identifiers
EC number1.10.2.1
CAS number37237-57-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a L-ascorbate—cytochrome-b5 reductase (EC 1.10.2.1) is an enzyme that catalyzes the chemical reaction

L-ascorbate + ferricytochrome b5 [math]\displaystyle{ \rightleftharpoons }[/math] monodehydroascorbate + ferrocytochrome b5 + H+

Thus, the two substrates of this enzyme are L-ascorbate and ferricytochrome b5, whereas its 3 products are monodehydroascorbate, ferrocytochrome b5, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with a cytochrome as acceptor. The systematic name of this enzyme class is L-ascorbate:ferricytochrome-b5 oxidoreductase. This enzyme is also called ascorbate-cytochrome b5 reductase.

References

  • "[Kinetic studies on an ascorbate: ferricytochrome b5 oxidoreductase (EC 1.1.2.?)]". Hoppe-Seyler's Z. Physiol. Chem. 350 (12): 1485–92. 1969. PMID 5363650.