Chemistry:Fluorenylmethyloxycarbonyl chloride
From HandWiki
Revision as of 02:15, 7 May 2022 by imported>MainAI (change)
![]() | |
![]() | |
Names | |
---|---|
Preferred IUPAC name
(9H-Fluoren-9-yl)methyl carbonochloridate | |
Other names
9-Fluorenylmethyl chloroformate; 9-Fluorenylmethoxycarbonyl chloride; Fmoc-chloride
| |
Identifiers | |
3D model (JSmol)
|
|
ChemSpider | |
EC Number |
|
PubChem CID
|
|
UNII | |
| |
| |
Properties | |
C15H11ClO2 | |
Molar mass | 258.70 g·mol−1 |
Melting point | 62 to 64 °C (144 to 147 °F; 335 to 337 K) |
Hazards | |
GHS pictograms | ![]() |
GHS Signal word | Danger |
H314 | |
P260, P261, P264, P270, P271, P280, P301+312, P301+330+331, P303+361+353, P304+312, P304+340, P305+351+338, P310, P312, P321, P330, P363, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
![]() ![]() ![]() | |
Infobox references | |
Tracking categories (test):
Fluorenylmethyloxycarbonyl chloride (Fmoc-Cl) is a chloroformate ester. It is used to introduce the fluorenylmethyloxycarbonyl protecting group as the Fmoc carbamate.
Preparation
This compound may be prepared by reacting 9-fluorenylmethanol with phosgene:[2]
References
- ↑ Fmoc chloride at Sigma-Aldrich
- ↑ Carpino, Louis A.; Han, Grace Y. (1972). "9-Fluorenylmethoxycarbonyl amino-protecting group". The Journal of Organic Chemistry 37 (22): 3404. doi:10.1021/jo00795a005.
![]() | Original source: https://en.wikipedia.org/wiki/Fluorenylmethyloxycarbonyl chloride.
Read more |