Moment closure

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In probability theory, moment closure is an approximation method used to estimate moments of a stochastic process.[1]

Introduction

Typically, differential equations describing the i-th moment will depend on the (i + 1)-st moment. To use moment closure, a level is chosen past which all cumulants are set to zero. This leaves a resulting closed system of equations which can be solved for the moments.[1] The approximation is particularly useful in models with a very large state space, such as stochastic population models.[1]

History

The moment closure approximation was first used by Goodman[2] and Whittle[3][4] who set all third and higher-order cumulants to be zero, approximating the population distribution with a normal distribution.[1]

In 2006, Singh and Hespanha proposed a closure which approximates the population distribution as a log-normal distribution to describe biochemical reactions.[5]

Applications

The approximation has been used successfully to model the spread of the Africanized bee in the Americas,[6] nematode infection in ruminants.[7] and quantum tunneling in ionization experiments.[8]

References

  1. 1.0 1.1 1.2 1.3 Gillespie, C. S. (2009). "Moment-closure approximations for mass-action models". IET Systems Biology 3 (1): 52–58. doi:10.1049/iet-syb:20070031. PMID 19154084. 
  2. Goodman, L. A. (1953). "Population Growth of the Sexes". Biometrics 9 (2): 212–225. doi:10.2307/3001852. 
  3. Whittle, P. (1957). "On the Use of the Normal Approximation in the Treatment of Stochastic Processes". Journal of the Royal Statistical Society 19 (2): 268–281. 
  4. Matis, T.; Guardiola, I. (2010). "Achieving Moment Closure through Cumulant Neglect". The Mathematica Journal 12. doi:10.3888/tmj.12-2. 
  5. Singh, A.; Hespanha, J. P. (2006). "Lognormal Moment Closures for Biochemical Reactions". Proceedings of the 45th IEEE Conference on Decision and Control. pp. 2063. doi:10.1109/CDC.2006.376994. ISBN 978-1-4244-0171-0. 
  6. Matis, J. H.; Kiffe, T. R. (1996). "On Approximating the Moments of the Equilibrium Distribution of a Stochastic Logistic Model". Biometrics 52 (3): 980–991. doi:10.2307/2533059. 
  7. Marion, G.; Renshaw, E.; Gibson, G. (1998). "Stochastic effects in a model of nematode infection in ruminants". Mathematical Medicine and Biology 15 (2): 97. doi:10.1093/imammb/15.2.97. 
  8. Baytaş, Bekir; Bojowald, Martin; Crowe, Sean (2018-12-17). "Canonical tunneling time in ionization experiments". Physical Review A (American Physical Society (APS)) 98 (6): 063417. doi:10.1103/physreva.98.063417. ISSN 2469-9926.