Biography:Antonio Siccardi
Antonio Siccardi MD | |
|---|---|
| Born | October 1, 1944 Varese |
| Nationality | Italian |
| Academic background | |
| Alma mater | University of Pavia |
| Academic work | |
| Discipline | Immunology Virology |
| Institutions | University of Milan |
Antonio G. Siccardi (born 1 October 1944, Varese) is an Italian immunologist and virologist.
Siccardi studied at the medical faculty of the University of Pavia and received his M.D. in 1968.[1] He later became associate professor for genetics (1973 to 1980) and then for microbiology (1974 to 1980).[2] After a short research trip to Rome as a full professor (1980 to 1982), he became full Professor for molecular immunology at the University of Milan from 1982 until today.[2] From 1990 to 1994 he was Operative Director of the DIBIT, San Raffaele Scientific Institute in Milan.[2] From 1991 to 1998 he coordinated the HIV/AIDS research at the Ospedale San Raffaele of the University of Milan.[2] He is (2015) professor for molecular immunology at the university of Milan and member of the board of the Istituto Nazionale di Genetica Molecolare (INGM).[3] From 2000 to 2008 he also was a deputy professor for genetics at the Faculty of Psychology of the Università Vita Salute San Raffaele in Milan and from 2006 to today (2015) deputy professor for History of Molecular Genetics at the Faculty of Biotechnology of the Università Vita Salute San Raffaele.[2]
Siccardi's areas of research comprise HIV,[4][5][6] influenza,[7] cancer (especially mesothelioma),[8][9] immunoglobulin E,[10] and vaccine design of recombinant Modified Vaccinia Ankara virus (MVA) or Fowlpoxvirus.[7] Siccardi developed a recombinant MVA-based vector for vaccination with different fluorescent reporter genes, which indicate the progress of genetic recombination with the transgene of an antigen (green, colorless, red).[7][11]
References
- ↑ biography of Antonio Siccardi at the AllergoOncology Symposium 2008.
- ↑ 2.0 2.1 2.2 2.3 2.4 CV of Antonio Siccardi. University of Milan.
- ↑ Jannis Kounellis per il charity project "all'Arte" (Italian). Men's Vogue Italy, May 22, 2014.
- ↑ Was zur Hölle sind Chemokine? (German). Interview with Robert Gallo, Der Spiegel no. 50, 1995.
- ↑ Grassi, F; Meneveri, R; Gullberg, M; Lopalco, L; Rossi, G. B.; Lanza, P; De Santis, C; Brattsand, G et al. (1991). "Human immunodeficiency virus type 1 gp120 mimics a hidden monomorphic epitope borne by class I major histocompatibility complex heavy chains". The Journal of Experimental Medicine 174 (1): 53–62. doi:10.1084/jem.174.1.53. PMID 1711567.
- ↑ Scarlatti, G; Tresoldi, E; Björndal, A; Fredriksson, R; Colognesi, C; Deng, H. K.; Malnati, M. S.; Plebani, A et al. (1997). "In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression". Nature Medicine 3 (11): 1259–65. doi:10.1038/nm1197-1259. PMID 9359702.
- ↑ 7.0 7.1 7.2 Soprana, E; Panigada, M; Knauf, M; Radaelli, A; Vigevani, L; Palini, A; Villa, C; Malnati, M et al. (2011). "Joint production of prime/boost pairs of Fowlpox Virus and Modified Vaccinia Ankara recombinants carrying the same transgene". Journal of Virological Methods 174 (1–2): 22–8. doi:10.1016/j.jviromet.2011.03.013. PMID 21419167.
- ↑ Guttinger, M; Guidi, F; Chinol, M; Reali, E; Veglia, F; Viale, G; Paganelli, G; Corti, A et al. (2000). "Adoptive immunotherapy by avidin-driven cytotoxic T lymphocyte-tumor bridging". Cancer Research 60 (15): 4211–5. PMID 10945632.
- ↑ Nigro, E. A.; Brini, A. T.; Soprana, E; Ambrosi, A; Dombrowicz, D; Siccardi, A. G.; Vangelista, L (2009). "Antitumor IgE adjuvanticity: Key role of Fc epsilon RI". The Journal of Immunology 183 (7): 4530–6. doi:10.4049/jimmunol.0900842. PMID 19748979.
- ↑ Vangelista, L; Soprana, E; Cesco-Gaspere, M; Mandiola, P; Di Lullo, G; Fucci, R. N.; Codazzi, F; Palini, A et al. (2005). "Membrane IgE binds and activates Fc epsilon RI in an antigen-independent manner". Journal of Immunology 174 (9): 5602–11. doi:10.4049/jimmunol.174.9.5602. PMID 15843559.
- ↑ Di Lullo, G; Soprana, E; Panigada, M; Palini, A; Erfle, V; Staib, C; Sutter, G; Siccardi, A. G. (2009). "Marker gene swapping facilitates recombinant Modified Vaccinia Virus Ankara production by host-range selection". Journal of Virological Methods 156 (1–2): 37–43. doi:10.1016/j.jviromet.2008.10.026. PMID 19038289.
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