Biography:René Peters (chemist)

From HandWiki

René Peters (born August 26, 1971, in Simmerath) is a German chemist and since 2008 Professor of Organic Chemistry at the University of Stuttgart.

Life and work

Peters studied chemistry at RWTH Aachen University from 1992 to 1997 and subsequently received his doctorate under Dieter Enders until 2000. This was followed by a stay as a postdoc at Harvard University with Yoshito Kishi as a DAAD scholarship holder. Between 2001 and 2004 he worked as a process research chemist at F. Hoffmann-La Roche LTD (Basel). From 2004 to 2008, Peters was an assistant professor at ETH Zurich. Since 2008 he has been Professor of Organic Chemistry at the University of Stuttgart.

The research team led by Prof. Peters contributes to the field of cooperative asymmetric catalysis.[1] The research is focused around the development of bi- and polyfunctional catalysts whose mode of action is inspired by enzymes, although the structure of the artificial catalysts is much simpler than those of enzymes. In the Peters catalysts, a Lewis acid often cooperates with charged, non-metallic functionalities such as ammonium,[2][3] pyridinium[4] or olium salts,[5][6] betaine units[7] and classical hydrogen bond donors.[8] Through the different catalyst functional groups, simultaneous activation and a precise spatial alignment of both reactants is often possible, so that high catalytic activity can be combined with very high stereocontrol.[9][10][11][12] In addition to the development of catalysts for asymmetric catalysis, the Peters research group investigates their mechanistic mode of action in an interdisciplinary approach.[13]

The research group is also known for its development of planar chiral metallacycles,[14][15][16][17] in which an intramolecular cooperation of two metal centers could often be used.[18][19][20][21]

References

  1. ↑ Peters, René (2015). Cooperative Catalysis – Designing Efficient Catalysts for Synthesis. Weinheim. 
  2. ↑ Brodbeck, Daniel; Broghammer, Florian; Meisner, Jan; Klepp, Julian; Garnier, Delphine; Frey, Wolfgang; Kästner, Johannes; Peters, René (2017-03-27). "An Aluminum Fluoride Complex with an Appended Ammonium Salt as an Exceptionally Active Cooperative Catalyst for the Asymmetric Carboxycyanation of Aldehydes" (in en). Angewandte Chemie International Edition 56 (14): 4056–4060. doi:10.1002/anie.201612493. PMID 28247498. https://onlinelibrary.wiley.com/doi/10.1002/anie.201612493. 
  3. ↑ Titze, Marvin; Heitkämper, Juliane; Junge, Thorsten; Kästner, Johannes; Peters, René (2021-03-01). "Highly Active Cooperative Lewis Acid—Ammonium Salt Catalyst for the Enantioselective Hydroboration of Ketones" (in en). Angewandte Chemie International Edition 60 (10): 5544–5553. doi:10.1002/anie.202012796. ISSN 1433-7851. PMID 33210781. 
  4. ↑ Kull, Thomas; Peters, René (2008-07-07). "Contact Ion Pair Directed Lewis Acid Catalysis: Asymmetric Synthesis of trans ‐Configured β‐Lactones" (in en). Angewandte Chemie International Edition 47 (29): 5461–5464. doi:10.1021/acscatal.1c05440. PMID 18537214. https://onlinelibrary.wiley.com/doi/10.1002/anie.200801143. 
  5. ↑ Mechler, Melanie; Peters, René (2015-08-24). "Diastereodivergent Asymmetric 1,4-Addition of Oxindoles to Nitroolefins by Using Polyfunctional Nickel-Hydrogen-Bond-Azolium Catalysts" (in en). Angewandte Chemie International Edition 54 (35): 10303–10307. doi:10.1002/anie.201502930. PMID 26118905. https://onlinelibrary.wiley.com/doi/10.1002/anie.201502930. 
  6. ↑ Schmid, Juliane; Junge, Thorsten; Lang, Johannes; Frey, Wolfgang; Peters, René (2019-04-08). "Polyfunctional Bis‐Lewis‐Acid‐/Bis‐Triazolium Catalysts for Stereoselective 1,4‐Additions of 2‐Oxindoles to Maleimides" (in en). Angewandte Chemie International Edition 58 (16): 5447–5451. doi:10.1002/anie.201814453. ISSN 1433-7851. PMID 30742732. https://onlinelibrary.wiley.com/doi/10.1002/anie.201814453. 
  7. ↑ Willig, Felix; Lang, Johannes; Hans, Andreas C.; Ringenberg, Mark R.; Pfeffer, Daniel; Frey, Wolfgang; Peters, René (2019-07-31). "Polyfunctional Imidazolium Aryloxide Betaine/Lewis Acid Catalysts as Tools for the Asymmetric Synthesis of Disfavored Diastereomers" (in en). Journal of the American Chemical Society 141 (30): 12029–12043. doi:10.1021/jacs.9b04902. ISSN 0002-7863. PMID 31268701. https://pubs.acs.org/doi/10.1021/jacs.9b04902. 
  8. ↑ Mechler, Melanie; Peters, René (2015-08-24). "Diastereodivergent Asymmetric 1,4-Addition of Oxindoles to Nitroolefins by Using Polyfunctional Nickel-Hydrogen-Bond-Azolium Catalysts" (in en). Angewandte Chemie International Edition 54 (35): 10303–10307. doi:10.1002/anie.201502930. PMID 26118905. https://onlinelibrary.wiley.com/doi/10.1002/anie.201502930. 
  9. ↑ Ye, Xinyi; Tan, Choon-Hong (2021). "Enantioselective transition metal catalysis directed by chiral cations" (in en). Chemical Science 12 (2): 533–539. doi:10.1039/D0SC05734G. ISSN 2041-6520. PMID 34163782. PMC 8179005. http://xlink.rsc.org/?DOI=D0SC05734G. 
  10. ↑ Fanourakis, Alexander; Docherty, Philip J.; Chuentragool, Padon; Phipps, Robert J. (2020-09-18). "Recent Developments in Enantioselective Transition Metal Catalysis Featuring Attractive Noncovalent Interactions between Ligand and Substrate" (in en). ACS Catalysis 10 (18): 10672–10714. doi:10.1021/acscatal.0c02957. ISSN 2155-5435. PMID 32983588. 
  11. ↑ Yuan, Yu-Chao; Mellah, Mohamed; Schulz, Emmanuelle; David, Olivier R. P. (2022-05-11). "Making Chiral Salen Complexes Work with Organocatalysts" (in en). Chemical Reviews 122 (9): 8841–8883. doi:10.1021/acs.chemrev.1c00912. ISSN 0009-2665. PMID 35266711. https://pubs.acs.org/doi/10.1021/acs.chemrev.1c00912. 
  12. ↑ Gong, Liu‐Zhu (2022-04-04) (in en). Asymmetric Organo‐Metal Catalysis: Concepts, Principles, and Applications (1 ed.). Wiley. doi:10.1002/9783527345939. ISBN 978-3-527-34592-2. https://onlinelibrary.wiley.com/doi/book/10.1002/9783527345939. 
  13. ↑ Heitkämper, Juliane; Herrmann, Justin; Titze, Marvin; Bauch, Soeren M.; Peters, René; Kästner, Johannes (2022-01-21). "Asymmetric Hydroboration of Ketones by Cooperative Lewis Acid–Onium Salt Catalysis: A Quantum Chemical and Microkinetic Study to Combine Theory and Experiment" (in en). ACS Catalysis 12 (2): 1497–1507. doi:10.1021/acscatal.1c05440. ISSN 2155-5435. https://pubs.acs.org/doi/10.1021/acscatal.1c05440. 
  14. ↑ Weiss, Matthias E.; Fischer, Daniel F.; Xin, Zhuo-qun; Jautze, Sascha; Schweizer, W. Bernd; Peters, René (2006-08-25). "Practical, Highly Active, and Enantioselective Ferrocenyl–Imidazoline Palladacycle Catalysts (FIPs) for the Aza-Claisen Rearrangement ofN-para-Methoxyphenyl Trifluoroacetimidates" (in en). Angewandte Chemie International Edition 45 (34): 5694–5698. doi:10.1002/anie.200601731. ISSN 1433-7851. PMID 16858701. https://onlinelibrary.wiley.com/doi/10.1002/anie.200601731. 
  15. ↑ Huang, Haoxi; Peters, René (2009-01-05). "A Highly Strained Planar-Chiral Platinacycle for Catalytic Activation of Internal Olefins in the Friedel-Crafts Alkylation of Indoles" (in en). Angewandte Chemie International Edition 48 (3): 604–606. doi:10.1002/anie.200804944. PMID 19072970. https://onlinelibrary.wiley.com/doi/10.1002/anie.200804944. 
  16. ↑ Schrapel, Carmen; Peters, René (2015-08-24). "Exogenous-Base-Free Palladacycle-Catalyzed Highly Enantioselective Arylation of Imines with Arylboroxines" (in en). Angewandte Chemie International Edition 54 (35): 10289–10293. doi:10.1002/anie.201501846. PMID 26088080. https://onlinelibrary.wiley.com/doi/10.1002/anie.201501846. 
  17. ↑ Pfeffer, Camilla; Probst, Patrick; Wannenmacher, Nick; Frey, Wolfgang; Peters, René (2022-08-26). "Direct Enantioselective Addition of Alkynes to Imines by a Highly Efficient Palladacycle Catalyst" (in en). Angewandte Chemie International Edition 61 (35): e202206835. doi:10.1002/anie.202206835. ISSN 1433-7851. PMID 35701311. 
  18. ↑ Maity, Ramananda; Birenheide, Bernhard S.; Breher, Frank; Sarkar, Biprajit (2021-05-19). "Cooperative Effects in Multimetallic Complexes Applied in Catalysis" (in en). ChemCatChem 13 (10): 2337–2370. doi:10.1002/cctc.202001951. ISSN 1867-3880. 
  19. ↑ Hickman, Daniel (2022-03-09). "Bispalladacycle-Catalyzed Allylation of Aldehydes" (in en-US). https://www.chemistryviews.org/details/ezine/11340402/Bispalladacycle-Catalyzed_Allylation_of_Aldehydes/. 
  20. ↑ Jautze, Sascha; Peters, René (2008-11-17). "Enantioselective Bimetallic Catalysis of Michael Additions Forming Quaternary Stereocenters" (in en). Angewandte Chemie International Edition 47 (48): 9284–9288. doi:10.1002/anie.200803539. ISSN 1433-7851. PMID 18956390. https://onlinelibrary.wiley.com/doi/10.1002/anie.200803539. 
  21. ↑ Weber, Manuel; Jautze, Sascha; Frey, Wolfgang; Peters, René (2010-09-08). "Bispalladacycle-Catalyzed Brønsted Acid/Base-Promoted Asymmetric Tandem Azlactone Formation−Michael Addition" (in en). Journal of the American Chemical Society 132 (35): 12222–12225. doi:10.1021/ja106088v. ISSN 0002-7863. PMID 20715774. https://pubs.acs.org/doi/10.1021/ja106088v. 

External links



Retrieved from "https://handwiki.org/wiki/index.php?title=Biography:René_Peters_(chemist)&oldid=3443647"