Biology:2'-Deamino-2'-hydroxyneamine transaminase
From HandWiki
Short description: Class of enzymes
| 2'-Deamino-2'-hydroxyneamine transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.6.1.94 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2'-Deamino-2'-hydroxyneamine transaminase (EC 2.6.1.94, kacL (gene)) is an enzyme with systematic name 2'-deamino-2'-hydroxyneamine:2-oxoglutarate aminotransferase.[1] This enzyme catalyses the following chemical reaction
- 2'-deamino-2'-hydroxyneamine + 2-oxoglutarate [math]\displaystyle{ \rightleftharpoons }[/math] 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate
The reaction occurs in vivo in the opposite direction.
References
- ↑ "Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology 7 (11): 843–52. October 2011. doi:10.1038/nchembio.671. PMID 21983602.
External links
- 2'-deamino-2'-hydroxyneamine+transaminase at the US National Library of Medicine Medical Subject Headings (MeSH)
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