Biology:2-hydroxy-1,4-benzoquinone reductase

From HandWiki
Short description: Class of enzymes
2-hydroxy-1,4-benzoquinone reductase
Identifiers
EC number1.6.5.7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

2-hydroxy-1,4-benzoquinone reductase (EC 1.6.5.7) is an enzyme that catalyzes the chemical reaction

  1. REDIRECT Template:Chemical reaction

The three substrates of this enzyme are hydroxy-1,4-benzoquinone, reduced nicotinamide adenine dinucleotide (NADH), and a proton. Its products are hydroxyquinol and oxidised NAD+.[1][2]

This enzyme participates in the metabolism of 2,4,5-trichlorophenoxyacetic acid in the bacteria Burkholderia cepacia.[2]

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is 2-hydroxy-1,4-benzoquinone:NADH oxidoreductase. Other names in common use include hydroxybenzoquinone reductase, 1,2,4-trihydroxybenzene:NAD oxidoreductase, and NADH:2-hydroxy-1,4-benzoquinone oxidoreductase.

References