Biology:2-hydroxy-1,4-benzoquinone reductase
| 2-hydroxy-1,4-benzoquinone reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.6.5.7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
2-hydroxy-1,4-benzoquinone reductase (EC 1.6.5.7) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
The three substrates of this enzyme are hydroxy-1,4-benzoquinone, reduced nicotinamide adenine dinucleotide (NADH), and a proton. Its products are hydroxyquinol and oxidised NAD+.[1][2]
This enzyme participates in the metabolism of 2,4,5-trichlorophenoxyacetic acid in the bacteria Burkholderia cepacia.[2]
Nomenclature
This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is 2-hydroxy-1,4-benzoquinone:NADH oxidoreductase. Other names in common use include hydroxybenzoquinone reductase, 1,2,4-trihydroxybenzene:NAD oxidoreductase, and NADH:2-hydroxy-1,4-benzoquinone oxidoreductase.
References
- ↑ Enzyme 1.6.5.7 at KEGG Pathway Database.
- ↑ 2.0 2.1 "Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100". Journal of Bacteriology 180 (17): 4667–75. September 1998. doi:10.1128/JB.180.17.4667-4675.1998. PMID 9721310.
