Biology:ARHGAP4
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Rho GTPase-activating protein 4 is an enzyme that in humans is encoded by the ARHGAP4 gene.[1][2] It has been shown to regulate cell motility and axonal outgrowth in vitro.[3]
References
- ↑ "An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells". Proc Natl Acad Sci U S A 93 (2): 695–9. Mar 1996. doi:10.1073/pnas.93.2.695. PMID 8570618. Bibcode: 1996PNAS...93..695T.
- ↑ "Entrez Gene: ARHGAP4 Rho GTPase activating protein 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=393.
- ↑ Vogt, DL; Gray, CD; Young Ws, 3rd; Orellana, SA; Malouf, AT (2007). "ARHGAP4 is a novel RhoGAP that mediates inhibition of cell motility and axon outgrowth". Molecular and Cellular Neurosciences 36 (3): 332–42. doi:10.1016/j.mcn.2007.07.004. PMID 17804252.
External links
- Human ARHGAP4 genome location and ARHGAP4 gene details page in the UCSC Genome Browser.
Further reading
- "Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae". Hum. Mol. Genet. 3 (7): 1061–7. 1995. doi:10.1093/hmg/3.7.1061. PMID 7981673.
- "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. 1996. doi:10.1093/dnares/2.4.167. PMID 8590280.
- "Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse". Genomics 44 (1): 8–14. 1997. doi:10.1006/geno.1997.4822. PMID 9286695.
- "A genome-wide survey of RAS transformation targets". Nat. Genet. 24 (2): 144–52. 2000. doi:10.1038/72799. PMID 10655059.
- "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. 2001. doi:10.1101/gr.143000. PMID 11076863.
- "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. 2001. doi:10.1093/embo-reports/kvd058. PMID 11256614.
- "Two novel types of contiguous gene deletion of the AVPR2 and ARHGAP4 genes in unrelated Japanese kindreds with nephrogenic diabetes insipidus". Hum. Mutat. 19 (1): 23–9. 2002. doi:10.1002/humu.10011. PMID 11754100.
- "p115 Rho GTPase activating protein interacts with MEKK1". J. Cell. Physiol. 192 (2): 200–8. 2002. doi:10.1002/jcp.10125. PMID 12115726.
- "Cloning of rat ARHGAP4/C1, a RhoGAP family member expressed in the nervous system that colocalizes with the Golgi complex and microtubules". Brain Res. Mol. Brain Res. 107 (1): 65–79. 2003. doi:10.1016/S0169-328X(02)00448-5. PMID 12414125. https://zenodo.org/record/1259925.
- "The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling". Nat. Cell Biol. 4 (12): 970–5. 2003. doi:10.1038/ncb886. PMID 12447388.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains". Int. J. Mol. Med. 11 (6): 791–7. 2004. doi:10.3892/ijmm.11.6.791. PMID 12736724.
- "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. 2004. doi:10.1101/gr.2576704. PMID 15489336.
- "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. 2006. doi:10.1093/nar/gkj139. PMID 16381901.
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