Biology:ATPC RNA motif

From HandWiki
Short description: Conserved RNA structure
ATPC RNA motif
ATPC secondary structure.jpg
Predicted secondary structure and sequence conservation of ATPC
Identifiers
SymbolATPC
RfamRF01067
Other data
RNA typeGene
Domain(s)Bacteria
SO0001263
PDB structuresPDBe

The ATPC RNA motif is a conserved RNA structure found in certain cyanobacteria.[1] It is apparently ubiquitous in Prochlorococcus marinus, and is present in many species in the genus Synechococcus. The RNA is always found within an operon encoding subunits of ATP synthase, and it is always located downstream of the gene encoding the A subunit of ATP synthase, and upstream of the C subunit gene. This location is consistent with a cis-regulatory element, but also with a non-coding RNA that is transcribed with the ATP synthase genes.

Simple RNA structures called stem-loops have been reported in the ATP synthase operons of various cyanobacteria,[2] but not structures such as the 3-stem junction that is the main feature of the ATPC RNA motif.

References

  1. "Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline". Nucleic Acids Res. 35 (14): 4809–4819. 2007. doi:10.1093/nar/gkm487. PMID 17621584. 
  2. Curtis SE (1988). "Structure, organization and expression of cyanobacterial ATP synthase genes". Photosynth. Res. 18 (1–2): 223–244. doi:10.1007/BF00042986. PMID 24425167. 

External links