Biology:ATPase ASNA1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
ATPase ASNA1 also known as arsenical pump-driving ATPase and arsenite-stimulated ATPase is an enzyme that in humans is encoded by the ASNA1 gene.[1][2]
Function
ASNA1 is the human homolog of the bacterial arsA gene. In E. coli, arsA ATPase is the catalytic component of a multisubunit oxyanion pump that is responsible for resistance to arsenicals and antimonials.[2]
Interactions
ASNA1 is found to interact with FAM71D according to STRING[3]
References
- ↑ "Isolation of the ATP-binding human homolog of the arsA component of the bacterial arsenite transporter". Genomics 36 (3): 486–91. Feb 1997. doi:10.1006/geno.1996.0494. PMID 8884272.
- ↑ 2.0 2.1 "Entrez Gene: ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=439.
- ↑ "STRING 10". http://string-db.org/newstring_cgi/show_network_section.pl.
External links
- Human ASNA1 genome location and ASNA1 gene details page in the UCSC Genome Browser.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Biochemical characterization of the human arsenite-stimulated ATPase (hASNA-I).". J. Biol. Chem. 273 (35): 22173–6. 1998. doi:10.1074/jbc.273.35.22173. PMID 9712828.
- "Dual cytoplasmic and nuclear distribution of the novel arsenite-stimulated human ATPase (hASNA-I).". J. Cell. Biochem. 71 (1): 1–10. 1998. doi:10.1002/(SICI)1097-4644(19981001)71:1<1::AID-JCB1>3.0.CO;2-#. PMID 9736449.
- "Chromosomal localization and genomic structure of the human arsenite-stimulated ATPase (hASNA-I).". Somat. Cell Mol. Genet. 24 (5): 307–11. 2000. doi:10.1023/B:SCAM.0000007134.16744.8b. PMID 10696239.
- "ASNA-1 positively regulates insulin secretion in C. elegans and mammalian cells.". Cell 128 (3): 577–87. 2007. doi:10.1016/j.cell.2006.12.031. PMID 17289575.
- "Identification of a targeting factor for posttranslational membrane protein insertion into the ER.". Cell 128 (6): 1147–59. 2007. doi:10.1016/j.cell.2007.01.036. PMID 17382883.
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