Biology:CEP164
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Centrosomal protein of 164 kDa, also known as CEP164, is a protein that in humans is encoded by the CEP164 gene.[1][2] Its function appears two be twofold: CEP164 is required for primary cilium formation.[3] Furthermore, it is an important component in the response to DNA damage by UV light.[4][5]
References
- ↑ "Entrez Gene: centrosomal protein 164kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22897.
- ↑ "Proteomic characterization of the human centrosome by protein correlation profiling". Nature 426 (6966): 570–4. December 2003. doi:10.1038/nature02166. PMID 14654843. Bibcode: 2003Natur.426..570A.
- ↑ Graser, S.; Stierhof, Y. -D.; Lavoie, S. B.; Gassner, O. S.; Lamla, S.; Le Clech, M.; Nigg, E. A. (2007). "Cep164, a novel centriole appendage protein required for primary cilium formation". The Journal of Cell Biology 179 (2): 321–30. doi:10.1083/jcb.200707181. PMID 17954613.
- ↑ Sivasubramaniam, S.; Sun, X.; Pan, Y. -R.; Wang, S. (2008). "Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1". Genes & Development 22 (5): 587–600. doi:10.1101/gad.1627708. PMID 18283122.
- ↑ Pan, YR; Lee, EY (2009). "UV-dependent interaction between Cep164 and XPA mediates localization of Cep164 at sites of DNA damage and UV sensitivity". Cell Cycle 8 (4): 655–64. doi:10.4161/cc.8.4.7844. PMID 19197159.
External links
- Human CEP164 genome location and CEP164 gene details page in the UCSC Genome Browser.
Further reading
- "Cep164, a novel centriole appendage protein required for primary cilium formation". J. Cell Biol. 179 (2): 321–30. 2007. doi:10.1083/jcb.200707181. PMID 17954613.
- "Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function". J. Cell Biol. 129 (6): 1617–28. 1995. doi:10.1083/jcb.129.6.1617. PMID 7790358.
- "Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation". Dev. Cell 5 (1): 113–25. 2003. doi:10.1016/S1534-5807(03)00193-X. PMID 12852856.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The Centrosomal Protein C-Nap1 Is Required for Cell Cycle–Regulated Centrosome Cohesion". J. Cell Biol. 151 (4): 837–46. 2000. doi:10.1083/jcb.151.4.837. PMID 11076968.
- "Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1". Genes Dev. 22 (5): 587–600. 2008. doi:10.1101/gad.1627708. PMID 18283122.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation". EMBO Rep. 7 (4): 418–24. 2006. doi:10.1038/sj.embor.7400639. PMID 16462731.
- "Assigning functions to genes: identification of S-phase expressed genes in Leishmania major based on post-transcriptional control elements". Nucleic Acids Res. 33 (13): 4235–42. 2005. doi:10.1093/nar/gki742. PMID 16052032.
- "UV-dependent interaction between Cep164 and XPA mediates localization of Cep164 at sites of DNA damage and UV sensitivity". Cell Cycle 8 (4): 655–64. 2009. doi:10.4161/cc.8.4.7844. PMID 19197159.
- "Centrosomal Proteins CG-NAP and Kendrin Provide Microtubule Nucleation Sites by Anchoring γ-Tubulin Ring Complex". Mol. Biol. Cell 13 (9): 3235–45. 2002. doi:10.1091/mbc.E02-02-0112. PMID 12221128.
 |  |
