Biology:Carboxybiotin decarboxylase
From HandWiki
| Carboxybiotin decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 7.2.4.1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Carboxybiotin decarboxylase (EC 7.2.4.1, MadB, carboxybiotin protein decarboxylase) is an enzyme with systematic name carboxybiotinyl-(protein) carboxy-lyase.[1][2] This enzyme catalyses the following chemical reaction
- a carboxybiotinyl-[protein] + n Na+in + H+out [math]\displaystyle{ \rightleftharpoons }[/math] CO2 + a biotinyl-[protein] + n Na+out (n = 1--2)
This enzyme is an integral membrane protein MadB from the anaerobic bacterium Malonomonas rubra.
Nomenclature
This enzyme was previously classified as EC 4.3.99.2.
References
- ↑ "Sequence of a gene cluster from Malonomonas rubra encoding components of the malonate decarboxylase Na+ pump and evidence for their function". European Journal of Biochemistry 245 (1): 103–15. April 1997. doi:10.1111/j.1432-1033.1997.00103.x. PMID 9128730.
- ↑ "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology 25 (1): 3–10. July 1997. doi:10.1046/j.1365-2958.1997.4611824.x. PMID 11902724.
External links
- Carboxybiotin+decarboxylase at the US National Library of Medicine Medical Subject Headings (MeSH)
 |  |
