Biology:Chondroitin-glucuronate 5-epimerase
From HandWiki
| chondroitin-glucuronate 5-epimerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.1.3.19 | ||||||||
| CAS number | 86417-91-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a chondroitin-glucuronate 5-epimerase (EC 5.1.3.19) is an enzyme that catalyzes the chemical reaction
- chondroitin D-glucuronate [math]\displaystyle{ \rightleftharpoons }[/math] dermatan L-iduronate
Hence, this enzyme has one substrate, chondroitin D-glucuronate, and one product, dermatan L-iduronate.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is chondroitin-D-glucuronate 5-epimerase. Other names in common use include polyglucuronate 5-epimerase, dermatan-sulfate 5-epimerase, urunosyl C-5 epimerase, and chondroitin D-glucuronosyl 5-epimerase. This enzyme participates in chondroitin sulfate biosynthesis.
References
- "Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase". Biochem. J. 201 (3): 489–93. 1982. doi:10.1042/bj2010489. PMID 7092807.
 |  |
