Biology:Crystal cells
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Short description: Type of blood cells in Drosophila
Crystal cells are one class of hemocytes (blood cells) in Drosophila melanogaster.[1] They play a primary role in wound healing and Reactive Oxygen Species Production. They heal wounds primarily by creating a melanized mass analogous to a human blood clot or scab.[2] Reactive oxygen species production is important for fighting off infections. Crystal cells are larger than plasmatocytes and smaller than Lamellocytes and can be identified by their prominent prophenoloxidasae (PPO) crystals, which are the main protein structures which allow them to melanize. Crystal cells have also been shown to carry oxygen.[3]
Crystal cells in Drosophila are analogous to oenocytoids in other insects.[4]
References
- ↑ Banerjee, Utpal; Girard, Juliet; Goins, Lauren; Spratford, Carrie (February 1, 2019). "Drosophila as a Genetic Model for Hematopoiesis". Genetics 211 (2): 367–417. doi:10.1534/genetics.118.300223. PMID 30733377. PMC 6366919. https://doi.org/10.1534/genetics.118.300223. Retrieved 12 April 2025.
- ↑ Gawa, Bidla; Malin, Lindgren; Theopold, Ulrich; Dushay, Mitchell (2005-01-01). "Hemolymph Coagulation and Phenoloxidase in Drosophila Larvae". Developmental & Comparitive Immunology 29 (8): 669–679. doi:10.1016/j.dci.2004.11.007. PMID 15854679. https://www.sciencedirect.com/science/article/pii/S0145305X04001958. Retrieved 12 April 2025.
- ↑ Shin, Mingyu; Chang, Eunji; Lee, Daewon; Kim, Nayun; Cho, Bumsik; Cha, Nuri; Koranteng, Ferdinand; Song, Ji-Joon et al. (2024-06-26). "Drosophila immune cells transport oxygen through PPO2 protein phase transition". Nature 631 (8020): 350–359. doi:10.1038/s41586-024-07583-x. PMID 38926577. Bibcode: 2024Natur.631..350S.
- ↑ Hultmark, Dan; Andó, István (August 3, 2022). "Hematopoietic plasticity mapped in Drosophila and other insects". eLife 11. doi:10.7554/eLife.78906. PMID 35920811.
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