Biology:Cytochrome b5, type A

Short description: Protein-coding gene in the species Homo sapiens

Cytochrome b5, form A (gene name CYB5A), is a human microsomal cytochrome b5.^[1]

Cytochrome b5 is a membrane bound hemoprotein which functions as an electron carrier for several membrane bound oxygenases. It has two isoforms produced by alternative splicing. Isoform 1 is bound to the cytoplasmic side of the endoplasmic reticulum. It has a C-terminal transmembrane alpha-helix. Isoform 2 was found in cytoplasm. Defects in CYB5A are the cause of type IV hereditary methemoglobinemia.

References

↑ "Entrez Gene: CYB5A Cytochrome b5, form A". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1528.

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