Biology:D-4-hydroxyphenylglycine transaminase

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D-4-hydroxyphenylglycine transaminase
Identifiers
EC number2.6.1.72
CAS number117444-05-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a D-4-hydroxyphenylglycine transaminase (EC 2.6.1.72) is an enzyme that catalyzes the chemical reaction

D-4-hydroxyphenylglycine + 2-oxoglutarate [math]\displaystyle{ \rightleftharpoons }[/math] 4-hydroxyphenylglyoxylate + L-glutamate

Thus, the two substrates of this enzyme are D-4-hydroxyphenylglycine and 2-oxoglutarate, whereas its two products are 4-hydroxyphenylglyoxylate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase. This enzyme is also called D-hydroxyphenylglycine aminotransferase. It employs one cofactor, pyridoxal phosphate.

References

  • "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. 2005. PMID 16525953. 
  • "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. 2005. PMID 16525953.