Biology:DHH phosphatase family

From HandWiki
DHH family
PDB 1i74 EBI.jpg
streptococcus mutans inorganic pyrophosphatase
Identifiers
SymbolDHH
PfamPF01368
InterProIPR001667
SCOP21i74 / SCOPe / SUPFAM

In molecular biology, the DHH phosphatase family is a family of putative phosphoesterases. The family includes Drosophila prune protein and bacterial RecJ exonuclease.[1] The RecJ protein of Escherichia coli plays an important role in a number of DNA repair and recombination pathways. RecJ catalyses processive degradation of single-stranded DNA in a 5'-to-3' direction. Sequences highly related to those encoding RecJ can be found in many of the eubacterial genomes sequenced to date.[2]

References

  1. "A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease". Trends in Biochemical Sciences 23 (1): 17–9. January 1998. doi:10.1016/s0968-0004(97)01162-6. PMID 9478130. 
  2. "A thermostable single-strand DNase from Methanococcus jannaschii related to the RecJ recombination and repair exonuclease from Escherichia coli". Journal of Bacteriology 182 (3): 607–12. February 2000. doi:10.1128/jb.182.3.607-612.2000. PMID 10633092. 
This article incorporates text from the public domain Pfam and InterPro: IPR001667