Biology:DUSP19

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Dual specificity protein phosphatase 19 is an enzyme that in humans is encoded by the DUSP19 gene.[1]


Interactions

DUSP19 has been shown to interact with ASK1[2] and MAP2K7.[2][3]

References

  1. "Entrez Gene: DUSP19 dual specificity phosphatase 19". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=142679. 
  2. 2.0 2.1 "Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway". The Journal of Biological Chemistry 277 (26): 23919–26. June 2002. doi:10.1074/jbc.M200838200. PMID 11959862. 
  3. "A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway". The Journal of Biological Chemistry 277 (26): 23909–18. June 2002. doi:10.1074/jbc.M200837200. PMID 11959861. 

Further reading

  • "Molecular cloning and characterization of a novel human protein phosphatase, LMW-DSP3". The International Journal of Biochemistry & Cell Biology 35 (2): 226–34. February 2003. doi:10.1016/S1357-2725(02)00127-9. PMID 12479873. 
  • "Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway". The Journal of Biological Chemistry 277 (26): 23919–26. June 2002. doi:10.1074/jbc.M200838200. PMID 11959862. 
  • "A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway". The Journal of Biological Chemistry 277 (26): 23909–18. June 2002. doi:10.1074/jbc.M200837200. PMID 11959861. 

External links

  • Overview of all the structural information available in the PDB for UniProt: Q8WTR2 (Human Dual specificity protein phosphatase 19 (DUSP19)) at the PDBe-KB.