Biology:EME1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Crossover junction endonuclease EME1 is an enzyme that in humans is encoded by the EME1 gene.[1][2] It forms a complex with MUS81 which resolves Holliday junctions.
References
- ↑ "Identification and characterization of the human mus81-eme1 endonuclease". J Biol Chem 278 (27): 25172–8. Jun 2003. doi:10.1074/jbc.M302882200. PMID 12721304.
- ↑ "Entrez Gene: EME1 essential meiotic endonuclease 1 homolog 1 (S. pombe)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=146956.
Further reading
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Identification and characterization of human MUS81-MMS4 structure-specific endonuclease". J. Biol. Chem. 278 (24): 21715–20. 2003. doi:10.1074/jbc.M302484200. PMID 12686547.
- Abraham J; Lemmers B; Hande MP et al. (2004). "Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells". EMBO J. 22 (22): 6137–47. doi:10.1093/emboj/cdg580. PMID 14609959.
- Blais V; Gao H; Elwell CA et al. (2004). "RNA Interference Inhibition of Mus81 Reduces Mitotic Recombination in Human Cells". Mol. Biol. Cell 15 (2): 552–62. doi:10.1091/mbc.E03-08-0580. PMID 14617801.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Beausoleil SA; Jedrychowski M; Schwartz D et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935. Bibcode: 2004PNAS..10112130B.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Rual JF; Venkatesan K; Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- Hiyama T; Katsura M; Yoshihara T et al. (2006). "Haploinsufficiency of the Mus81–Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells". Nucleic Acids Res. 34 (3): 880–92. doi:10.1093/nar/gkj495. PMID 16456034.
- Olsen JV; Blagoev B; Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
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