Biology:Exosome component 8

Generic protein structure example

Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex.

Interactions

Exosome component 8 has been shown to interact with:

• Exosome component 5 and
• Exosome component 6.

Further reading

• Andersen JS; Lam YW; Leung AK et al. (2005). "Nucleolar proteome dynamics". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. Bibcode: 2005Natur.433...77A. 
• Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
• "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. 2004. doi:10.1101/gr.2122004. PMID 15231747. 
• Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring". J. Mol. Biol. 323 (4): 653–63. 2002. doi:10.1016/S0022-2836(02)00947-6. PMID 12419256. 
• "A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3′→5′ exoribonuclease activity". Proc. Natl. Acad. Sci. U.S.A. 99 (8): 5295–300. 2002. doi:10.1073/pnas.072083699. PMID 11929972. 
• "Protein-protein interactions of hCsl4p with other human exosome subunits". J. Mol. Biol. 315 (4): 809–18. 2002. doi:10.1006/jmbi.2001.5265. PMID 11812149. 
• Chen CY; Gherzi R; Ong SE et al. (2002). "AU binding proteins recruit the exosome to degrade ARE-containing mRNAs". Cell 107 (4): 451–64. doi:10.1016/S0092-8674(01)00578-5. PMID 11719186. 
• "Protein–protein interactions with subunits of human nuclear RNase P". Proc. Natl. Acad. Sci. U.S.A. 98 (3): 920–5. 2001. doi:10.1073/pnas.021561498. PMID 11158571. 
• Brouwer R; Allmang C; Raijmakers R et al. (2001). "Three novel components of the human exosome". J. Biol. Chem. 276 (9): 6177–84. doi:10.1074/jbc.M007603200. PMID 11110791. 
• "Using the yeast two-hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth". Mol. Microbiol. 27 (1): 171–86. 1998. doi:10.1046/j.1365-2958.1998.00670.x. PMID 9466265.