Biology:FinP

From HandWiki
FinP
RF00107.jpg
Predicted secondary structure and sequence conservation of FinP
Identifiers
SymbolFinP
RfamRF00107
Other data
RNA typeGene
Domain(s)Bacteria
SO0000644
PDB structuresPDBe

FinP encodes an antisense non-coding RNA gene that is complementary to part of the TraJ 5' UTR. The FinOP system regulates the transfer of F-like plasmids. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.[1][2]

References

  1. "Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E". Journal of Molecular Biology 285 (4): 1457–1473. January 1999. doi:10.1006/jmbi.1998.2404. PMID 9917389. 
  2. "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". The EMBO Journal 22 (23): 6346–6355. December 2003. doi:10.1093/emboj/cdg607. PMID 14633993. 

External links