Biology:Ftx (gene)
From HandWiki
Short description: Genetic element in the species Homo sapiens
 Generic protein structure example |
In molecular biology, FTX transcript, XIST regulator (non-protein coding), also known as FTX (Five prime to Xist), is a long non-coding RNA. In humans, it is located on the X chromosome. It was identified during sequence analysis of the X inactivation centre, surrounding the XIST gene.[1] FTX contains several microRNAs within its introns.[2] It upregulates expression of XIST, and inhibits DNA methylation of the XIST promoter.[2]
See also
- Long noncoding RNA
References
- ↑ "Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine.". Genome Res 12 (6): 894–908. 2002. doi:10.1101/gr.152902. PMID 12045143.
- ↑ 2.0 2.1 "Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region.". Hum Mol Genet 20 (4): 705–718. 2011. doi:10.1093/hmg/ddq516. PMID 21118898.
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