Biology:Galactocerebroside

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A galactocerebroside

A galactocerebroside (or galactosylceramide) is a type of cerebroside consisting of a ceramide with a galactose residue at the 1-hydroxyl moiety.

The galactose is cleaved by galactosylceramidase.

Galactocerebroside is a marker for oligodendrocytes in the brain, whether or not they form myelin.[1][2]

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References

  1. Raff, Martin C.; Mirsky, Rhona; Fields, K. L.; Lisak, Robert P.; Dorfman, Susan H.; Silberberg, Donald H.; Gregson, N. A.; Leibowitz, Sidney et al. (1978). "Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture". Nature 274 (5673): 813–816. doi:10.1038/274813a0. 
  2. Jessen, K. R.; Morgan, L.; Brammer, M.; Mirsky, R. (1985). "Galactocerebroside is expressed by non-myelin-forming Schwann cells in situ". The Journal of Cell Biology 101 (3): 1135–1143. doi:10.1083/jcb.101.3.1135. PMID 3897245. 

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