Biology:HSD17B14
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
17β-Hydroxysteroid dehydrogenase type 14 also known as 17β-HSD type 14 or 17βHSD14 is an enzyme that in humans is encoded by the HSD17B14 gene.[1][2]
17βHSD14 catalyzes the stereospecific oxidation and reduction of the 17β carbon atom of androgens and estrogens using NAD(P)(H) as a cofactor. It is primarily expressed in glandular epithelial tissues of breast, ovary, and testis.[3]
References
- ↑ Zhu, Yuan-Shan; Imperato-McGinley, Julianne L. (9 November 2016). "4.02: Disorders of Sexual Development in Males: Molecular Genetics, Epigenetics, Gender Identity, and Cognition". Hormones, Brain and Behavior. 4: Clinical Important Effects of Hormones on Brain and Behavior. Elsevier Science. pp. 69. ISBN 978-0-12-803608-2. https://books.google.com/books?id=NT8oCwAAQBAJ&pg=RA3-PA69.
- ↑ Zanders, Edward D. (9 November 2015). Human Drug Targets: A Compendium for Pharmaceutical Discovery. John Wiley & Sons. pp. 257–. ISBN 978-1-118-84985-9. https://books.google.com/books?id=airvCQAAQBAJ&pg=PA257.
- ↑ "Expression patterns of 17β-hydroxysteroid dehydrogenase 14 in human tissues". Hormone and Metabolic Research 44 (13): 949–56. 2012. doi:10.1055/s-0032-1321815. PMID 22864907. http://liu.diva-portal.org/smash/get/diva2:561150/FULLTEXT01.
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