Biology:Hydrogenase (NAD+, ferredoxin)
From HandWiki
| Hydrogenase (NAD+, ferredoxin) | |||||||||
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| Identifiers | |||||||||
| EC number | 1.12.1.4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Hydrogenase (NAD+, ferredoxin) (EC 1.12.1.4, bifurcating [FeFe] hydrogenase) is an enzyme with systematic name hydrogen:NAD+, ferredoxin oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- 2 H2 + NAD+ + 2 oxidized ferredoxin [math]\displaystyle{ \rightleftharpoons }[/math] 5 H+ + NADH + 2 reduced ferredoxin
The enzyme from Thermotoga maritima contains a [Fe-Fe] cluster (H-cluster) and iron-sulfur clusters. I
References
- ↑ "The hyperthermophilic bacterium, Thermotoga maritima, contains an unusually complex iron-hydrogenase: amino acid sequence analyses versus biochemical characterization". Biochimica et Biophysica Acta 1412 (3): 212–29. August 1999. doi:10.1016/s0005-2728(99)00062-6. PMID 10482784.
- ↑ "The iron-hydrogenase of Thermotoga maritima utilizes ferredoxin and NADH synergistically: a new perspective on anaerobic hydrogen production". Journal of Bacteriology 191 (13): 4451–7. July 2009. doi:10.1128/JB.01582-08. PMID 19411328.
External links
- Hydrogenase+(NAD+,+ferredoxin) at the US National Library of Medicine Medical Subject Headings (MeSH)
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