Biology:Itruvone
From HandWiki
Short description: Experimental drug
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| Other names | PH10; PH10A; PH10 NS; Pregn-4-en-20-yn-3-one |
| Routes of administration | Intranasal (spray) |
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| Formula | C21H28O |
| Molar mass | 296.454 g·mol−1 |
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Itruvone (INN; developmental code name PH10), also known as pregn-4-en-20-yn-3-one, is a vomeropherine which is under development by VistaGen Therapeutics as a nasal spray for the treatment of major depressive disorder.[1][2][3][4][5][6]
See also
References
- ↑ "PH-10 Nasal Spray". AdisInsight. Springer Nature Switzerland AG. http://adisinsight.springer.com/drugs/800043336.
- ↑ "Neural circuits of anxiolytic and antidepressant pherine molecules". CNS Spectr 27 (1): 66–72. February 2022. doi:10.1017/S109285292000190X. PMID 33092667.
- ↑ "VistaGen Therapeutics Acquires Worldwide Rights to Develop and Commercialize PH10, a First-in-Class Intranasally Administered Neuroactive Steroid with Rapid-onset Antidepressant Effects for Major Depressive Disorder Demonstrated in Phase 2a Study :: VistaGen Therapeutics, Inc. (VTGN)" (in en). https://www.vistagen.com/news-media/press-releases/detail/100/vistagen-therapeutics-acquires-worldwide-rights-to-develop.
- ↑ "Health Care Digest: A small biotech goes head first, Gilead's lower tax rate and more". San Francisco Business Times. October 29, 2018. https://www.bizjournals.com/sanfrancisco/news/2018/10/29/depression-ketamine-vistagen-vtgn-gilead-taxes.html.
- ↑ PH 10 may be a new rapidly acting intranasally administered antidepressant. American Society of Clinical Psychopharmacology (ASCP) Annual Meeting, Miami, FL. 2013.
- ↑ Jancin, Bruce (2013). "Novel intranasal antidepressant shows results after 1 week". Clinical Psychiatry News. http://www.clinicalpsychiatrynews.com/specialty-focus/depression/single-article-page/novel-intranasal-antidepressant-shows-results-after-1-week/f88c1d176634f223babe0169c6f4af2f.html. Retrieved 13 January 2016.
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