Biology:KCNQ1DN
From HandWiki
 Generic protein structure example |
| KCNQ1 downstream neighbour | |
|---|---|
 Predicted secondary structure and sequence conservation of KCNQ1DN | |
| Identifiers | |
| Symbol | KCNQ1DN |
| Rfam | RF01961 |
| Other data | |
| RNA type | Gene; |
| Domain(s) | Eukaryota; |
| SO | 0001463 |
| PDB structures | PDBe |
KCNQ1 downstream neighbour (KCNQ1DN) is a long non-coding RNA gene. In humans, it is located on chromosome 11p15.5 between the CDKN1C and KCNQ1 genes. It is an imprinted gene, expressed from the maternal allele. Reduced expression of KCNQ1DN is observed in Wilms' tumours.[1]
See also
- Long noncoding RNA
References
- ↑ "A novel imprinted gene, KCNQ1DN, within the WT2 critical region of human chromosome 11p15.5 and its reduced expression in Wilms' tumors". J. Biochem. 128 (5): 847–853. November 2000. doi:10.1093/oxfordjournals.jbchem.a022823. PMID 11056398.
Further reading
- "Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting.". Hum. Mol. Genet. 9 (18): 2691–2706. 2000. doi:10.1093/hmg/9.18.2691. PMID 11063728.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–2127. 2004. doi:10.1101/gr.2596504. PMID 15489334.
External links
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