Biology:Lactate permease family
From HandWiki
| Lactate permease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | LctP | ||||||||
| Pfam | PF02652 | ||||||||
| InterPro | IPR003804 | ||||||||
| TCDB | 2.A.14 | ||||||||
| |||||||||
The lactate permease (LctP) family (TC# 2.A.14) is a family of transport proteins belonging to the ion transporter (IT) superfamily.[1]
Function
Characterized members of this family possess 15-18 transmembrane segments (TMSs) and are roughly 460-565 amino acyl residues in length.
General transport reaction
Transport reactions catalyzed by functionally characterized members of the LctP family include:[2]
D- or L-lactate or glycolate (out) + H+ (out) → D- or L-lactate or glycolate (in) + H+ (in).
References
- ↑ "The ion transporter superfamily". Biochimica et Biophysica Acta (BBA) - Biomembranes 1618 (1): 79–92. December 2003. doi:10.1016/j.bbamem.2003.10.010. PMID 14643936.
- ↑ "2.A.14 The Lactate Permease (LctP) Family". http://www.tcdb.org/search/result.php?tc=2.A.14.
Further reading
- "Membrane transport metabolons". Biochimica et Biophysica Acta (BBA) - Biomembranes 1818 (11): 2687–706. November 2012. doi:10.1016/j.bbamem.2012.06.007. PMID 22705263.
- "Transport of L-Lactate, D-Lactate, and glycolate by the LldP and GlcA membrane carriers of Escherichia coli". Biochemical and Biophysical Research Communications 290 (2): 824–9. January 2002. doi:10.1006/bbrc.2001.6255. PMID 11785976.
- "TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters". Microbiology 145 (12): 3431–45. December 1999. doi:10.1099/00221287-145-12-3431. PMID 10627041.
- "Phylogenetic characterization of novel transport protein families revealed by genome analyses". Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes 1422 (1): 1–56. February 1999. doi:10.1016/s0304-4157(98)00023-9. PMID 10082980.
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