Biology:Mir-11 microRNA precursor family

From HandWiki
mir-11
Identifiers
Symbolmir-11
RfamRF00813
miRBase family2
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

In molecular biology mir-11 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. There is an evidence to suggest that miR-11 plays a role in apoptosis.[1]

Alignment has shown that miR-11 shares the same family motif as miR-2b and miR-6, together making up the mir-2 clan. There is however little similarity in the 3' ends between these clan members.

See also

References

  1. Ge, W; Chen, YW; Weng, R; Lim, SF; Buescher, M; Zhang, R; Cohen, SM (May 2012). "Overlapping functions of microRNAs in control of apoptosis during Drosophila embryogenesis.". Cell Death & Differentiation 19 (5): 839–46. doi:10.1038/cdd.2011.161. PMID 22095284. 

Further reading

External links




  1. Truscott, M.; Islam, A. B. M. M. K.; Lopez-Bigas, N.; Frolov, M. V. (2011). "Mir-11 limits the proapoptotic function of its host gene, dE2f1". Genes & Development 25 (17): 1820–1834. doi:10.1101/gad.16947411. PMID 21856777. 
  2. "Differential expression of microRNA species in a freeze tolerant insect, Eurosta solidaginis.". Cryobiology 65 (3): 210–4. 2012. doi:10.1016/j.cryobiol.2012.06.005. PMID 22765989.