Biology:Mir-633 microRNA precursor family
From HandWiki
| mir-633 | |
|---|---|
| Identifiers | |
| Symbol | mir-633 |
| Rfam | RF01028 |
| miRBase family | MIPF0000546 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-633 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
miR-633 in Leukaemia
miR-633 has been linked to acute lymphoblastic leukaemia (ALL) and as having a potential role in the development of leukaemia, due to abnormal expression in ALL subjects.[1] It may be of use for prediction of relapse potential and in development of personalised leukaemia treatments.
Progesterone regulation
miR-633 expression in endometrial carcinoma cells upon treatment with progesterone saw a 50% decrease in expression levels. These point towards a possible critical role of miR-633, alongside other miRNAs, in the regulation of posttranscriptional gene expression on progesterone treatment.[2]
See also
References
- ↑ "[Association of miRNAs expression profiles with prognosis and relapse in childhood acute lymphoblastic leukemia."]. Zhonghua Xue Ye Xue Za Zhi 32 (3): 178–81. 2011. PMID 21535956. https://pubmed.ncbi.nlm.nih.gov/21535956.
- ↑ "Identification of differentially expressed microRNAs in endometrial cancer cells after progesterone treatment.". Int J Gynecol Cancer 22 (4): 561–5. 2012. doi:10.1097/IGC.0b013e31824927db. PMID 22543862. https://pubmed.ncbi.nlm.nih.gov/22543862.
External links
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