Biology:Monocarboxylate transporter 10
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Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
Monocarboxylate transporter 10 (MCT 10), also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 (TAT1) and solute carrier family 16 member 10 (SLC16A10), is a protein that in humans is encoded by the SLC16A10 gene.[1][2][3] SLC16A10 is a member of the solute carrier family.
Function
SLC16A10 mediates Na+-independent transport of tryptophan, tyrosine, phenylalanine, and L-DOPA.[3]
See also
References
- ↑ "Entrez Gene: solute carrier family 16". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117247.
- ↑ "Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters". J. Biol. Chem. 276 (20): 17221–8. May 2001. doi:10.1074/jbc.M009462200. PMID 11278508.
- ↑ 3.0 3.1 "The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location". Genomics 79 (1): 95–103. January 2002. doi:10.1006/geno.2001.6678. PMID 11827462.
Further reading
- "Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling.". J. Biol. Chem. 276 (23): 20309–15. 2001. doi:10.1074/jbc.M011740200. PMID 11278976.
- "Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10.". Mol. Endocrinol. 22 (6): 1357–69. 2008. doi:10.1210/me.2007-0112. PMID 18337592.
- "Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction.". Placenta 31 (4): 295–304. 2010. doi:10.1016/j.placenta.2010.01.013. PMID 20167367. http://www.zora.uzh.ch/id/eprint/33687/3/Stieger_TH_transporters-2.pdf. Retrieved 2019-08-16.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- Bröer S (2008). "Amino acid transport across mammalian intestinal and renal epithelia.". Physiol. Rev. 88 (1): 249–86. doi:10.1152/physrev.00018.2006. PMID 18195088. https://semanticscholar.org/paper/0ed966360f9302bb910bbe0daa17aea6da1258f9.
- "Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule.". Arch. Pharm. Res. 28 (4): 421–32. 2005. doi:10.1007/BF02977671. PMID 15918515.
- "The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.". Pflügers Arch. 447 (5): 619–28. 2004. doi:10.1007/s00424-003-1067-2. PMID 12739169.
Original source: https://en.wikipedia.org/wiki/Monocarboxylate transporter 10.
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