Biology:Moricin
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Moricin | |||||||||
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![]() Solution structure of antibacterial peptide (moricin)[1] | |||||||||
Identifiers | |||||||||
Symbol | Moricin | ||||||||
Pfam | PF06451 | ||||||||
InterPro | IPR009456 | ||||||||
SCOP2 | 1kv4 / SCOPe / SUPFAM | ||||||||
OPM superfamily | 151 | ||||||||
OPM protein | 1kv4 | ||||||||
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Moricin is a highly basic antibacterial peptide that was isolated from the silkworm Bombyx mori.[1] It consists of a long alpha-helix with 8 turns from a 42 amino acid sequence over almost the entire protein.[1] The amphipathic N-terminal segment of the alpha- helix is mainly responsible for the increase in permeability of the bacterial membrane which kills the bacteria.[1] Moricin functions as an antibacterial peptide against Gram-positive and Gram-negative bacteria, with its main activity being towards Gram-positive bacteria.[1]
References
External links
![]() | Original source: https://en.wikipedia.org/wiki/Moricin.
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