Biology:MvirDB

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Short description: Biological database
MvirDB
Content
DescriptionA database of toxins, virulence factors and antibiotic resistance genes
Data types
captured		Toxins, Virulence Factors and Antibiotic resistance genes
OrganismsBacteria
Contact
Primary citationPMID 17090593
Access
Websitemvirdb.llnl.gov
Miscellaneous
Bookmarkable
entities		yes

In molecular biology, MvirDB is a publicly available database that stores information on toxins, virulence factors and antibiotic resistance genes.[1] Sources that this database uses for DNA and protein information include: Tox-Prot,[2] SCORPION,[3] the PRINTS Virulence Factors,[4][5] VFDB,[6] TVFac, Islander,[7] ARGO[8] and VIDA.[9] The database provides a BLAST tool that allows the user to query their sequence against all DNA and protein sequences in MvirDB. Information on virulence factors can be obtained from the usage of the provided browser tool. Once the browser tool is used, the results are returned as a readable table that is organized by ascending E-Values, each of which are hyperlinked to their related page. MvirDB is implemented in an Oracle 10g relational database.[1]

See also

References

  1. ↑ 1.0 1.1 Zhou, C. E.; Smith, J.; Lam, M.; Zemla, A.; Dyer, M. D.; Slezak, T. (2007-01-03). "MvirDB--a microbial database of protein toxins, virulence factors and antibiotic resistance genes for bio-defence applications". Nucleic Acids Research 35 (Database): D391–D394. doi:10.1093/nar/gkl791. ISSN 0305-1048. PMID 17090593. 
  2. ↑ Jungo, Florence; Bairoch, Amos (March 2005). "Tox-Prot, the toxin protein annotation program of the Swiss-Prot protein knowledgebase". Toxicon 45 (3): 293–301. doi:10.1016/j.toxicon.2004.10.018. ISSN 0041-0101. PMID 15683867. 
  3. ↑ Srinivasan, K.N.; Gopalakrishnakone, P.; Tan, P.T.; Chew, K.C.; Cheng, B.; Kini, R.M.; Koh, J.L.Y.; Seah, S.H. et al. (January 2002). "SCORPION, a molecular database of scorpion toxins". Toxicon 40 (1): 23–31. doi:10.1016/s0041-0101(01)00182-9. ISSN 0041-0101. PMID 11602275. 
  4. ↑ "Author Index Vol. 15, No. 1, 2008". Journal of Molecular Microbiology and Biotechnology 15 (1): 65. 2008. doi:10.1159/000121450. ISSN 1464-1801. 
  5. ↑ Attwood, Teresa K.; Bradley, Paul M.; Gaulton, Anna; Maudling, Neil; Mitchell, Alexander L.; Moulton, Georgina (2005-04-15), The PRINTS protein fingerprint database: functional and evolutionary applications, John Wiley & Sons, Ltd, doi:10.1002/047001153x.g306301, ISBN 047001153X 
  6. ↑ Chen, L. (2004-12-17). "VFDB: a reference database for bacterial virulence factors". Nucleic Acids Research 33 (Database issue): D325–D328. doi:10.1093/nar/gki008. ISSN 1362-4962. PMID 15608208. 
  7. ↑ Mantri, Y. (2004-01-01). "Islander: a database of integrative islands in prokaryotic genomes, the associated integrases and their DNA site specificities". Nucleic Acids Research 32 (90001): 55D–58. doi:10.1093/nar/gkh059. ISSN 1362-4962. PMID 14681358. 
  8. ↑ Scaria, Joy; Chandramouli, Umamaheswaran; Verma, Sanjay Kumar (2005-02-01). "Antibiotic Resistance Genes Online (ARGO): A Database on vancomycin and b-lactam resistance genes". Bioinformation 1 (1): 5–7. doi:10.6026/97320630001005. ISSN 0973-8894. PMID 17597841. 
  9. ↑ Yeats, C.; Lees, J.; Reid, A.; Kellam, P.; Martin, N.; Liu, X.; Orengo, C. (2007-12-23). "Gene3D: comprehensive structural and functional annotation of genomes". Nucleic Acids Research 36 (Database): D414–D418. doi:10.1093/nar/gkm1019. ISSN 0305-1048. PMID 18032434. 



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