Biology:NETO1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Neuropilin (NRP) and tolloid (TLL)-like 1 is a protein that in humans is encoded by the NETO1 gene.[1]
Function
This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].[2]
References
- ↑ "Entrez Gene: Neuropilin (NRP) and tolloid (TLL)-like 1". https://www.ncbi.nlm.nih.gov/gene/81832.
- ↑ "NM_032970.4 Homo sapiens SEC22 homolog C (SEC22C), transcript variant 1, mRNA". National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/nuccore/NM_032970.4.
Further reading
- "Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning". PLOS Biology 7 (2). February 2009. doi:10.1371/journal.pbio.1000041. PMID 19243221.
- "A case control association study and cognitive function analysis of neuropilin and tolloid-like 1 gene and schizophrenia in the Japanese population". PLOS ONE 6 (12). 2011. doi:10.1371/journal.pone.0028929. PMID 22205981. Bibcode: 2011PLoSO...628929B.
- "A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain". Gene 286 (2): 223–31. March 2002. doi:10.1016/s0378-1119(02)00438-9. PMID 11943477.
- "The genetic architecture of economic and political preferences". Proceedings of the National Academy of Sciences of the United States of America 109 (21): 8026–31. May 2012. doi:10.1073/pnas.1120666109. PMID 22566634. PMC 3361436. Bibcode: 2012PNAS..109.8026B. https://dash.harvard.edu/bitstream/handle/1/10121961/Benjamin_GeneticArchitecture.pdf?sequence=1.
- "Genetic determinants of autism in individuals with deletions of 18q". Human Genetics 128 (2): 155–64. August 2010. doi:10.1007/s00439-010-0839-y. PMID 20499253.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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