Biology:NLRP8
From HandWiki
NLRP8, short for NOD-like receptor family pyrin domain containing 8, is an intracellular protein that is expressed in the ovaries, testes, and preimplantation embryos of mammals.[1][2] It is also known as NALP8, NOD16, PAN4, and CLR19.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.
References
- ↑ "Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos". Biol. Reprod. 74 (3): 577–84. March 2006. doi:10.1095/biolreprod.105.045096. PMID 16339045.
- ↑ "Evolution and functional divergence of NLRP genes in mammalian reproductive systems". BMC Evol. Biol. 9 (1). 2009. doi:10.1186/1471-2148-9-202. PMID 19682372. Bibcode: 2009BMCEE...9..202T.
Further reading
- "Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.". Cancer Res. 68 (24): 10178–86. 2008. doi:10.1158/0008-5472.CAN-08-2221. PMID 19074885. https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_1_from_Genetic_Variants_in_Apoptosis_and_Immunoregulation-Related_Genes_Are_Associated_with_Risk_of_Chronic_Lymphocytic_Leukemia/22376466/1/files/39821778.pdf.
- "NODs: intracellular proteins involved in inflammation and apoptosis.". Nat. Rev. Immunol. 3 (5): 371–82. 2003. doi:10.1038/nri1086. PMID 12766759.
- "NALPs: a novel protein family involved in inflammation.". Nat. Rev. Mol. Cell Biol. 4 (2): 95–104. 2003. doi:10.1038/nrm1019. PMID 12563287.
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