Biology:OTUB2
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 Generic protein structure example |
Ubiquitin thioesterase OTUB2 is an enzyme that in humans is encoded by the OTUB2 gene.[1][2]
Otubains are deubiquitinating cysteine proteases (DUBs; see MIM 602519) that belong to the ovarian tumor (OTU) protein superfamily. Like other DUBs, otubains cleave proteins precisely at the ubiquitin (UB; see MIM 191339)-protein bond.[2]
References
- ↑ "Otubains: a new family of cysteine proteases in the ubiquitin pathway". EMBO Rep 4 (5): 517–22. Apr 2003. doi:10.1038/sj.embor.embor824. PMID 12704427.
- ↑ 2.0 2.1 "Entrez Gene: OTUB2 OTU domain, ubiquitin aldehyde binding 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=78990.
Further reading
- "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Crystal structure of human otubain 2.". EMBO Rep. 5 (8): 783–8. 2005. doi:10.1038/sj.embor.7400201. PMID 15258613.
- "Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.". Mamm. Genome 15 (3): 162–78. 2004. doi:10.1007/s00335-003-2311-y. PMID 15014966.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The DNA sequence and analysis of human chromosome 14.". Nature 421 (6923): 601–7. 2003. doi:10.1038/nature01348. PMID 12508121. Bibcode: 2003Natur.421..601H.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
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