Biology:PIK3C3
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme subunit that in humans is encoded by the PIK3C3 gene.[1][2] It's a class III phosphoinositide 3-kinase.
References
- ↑ "A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system". EMBO J 14 (14): 3339–48. Sep 1995. doi:10.1002/j.1460-2075.1995.tb07340.x. PMID 7628435.
- ↑ "Entrez Gene: PIK3C3 phosphoinositide-3-kinase, class 3". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=5289.
Further reading
- "Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.". J. Leukoc. Biol. 74 (5): 676–82. 2004. doi:10.1189/jlb.0503206. PMID 12960231.
- "The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes.". Mol. Cell. Biol. 13 (12): 7408–17. 1994. doi:10.1128/mcb.13.12.7408. PMID 7504174.
- "Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.". J. Biol. Chem. 271 (38): 22961–4. 1996. doi:10.1074/jbc.271.38.22961. PMID 8798481.
- "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. 1997. doi:10.1101/gr.6.9.791. PMID 8889548.
- "Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex.". J. Biol. Chem. 272 (4): 2477–85. 1997. doi:10.1074/jbc.272.4.2477. PMID 8999962.
- "Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity.". Eur. J. Immunol. 27 (9): 2457–65. 1997. doi:10.1002/eji.1830270946. PMID 9341793.
- "Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells.". Eur. J. Immunol. 27 (11): 2805–11. 1998. doi:10.1002/eji.1830271110. PMID 9394803.
- "Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.". Biochem. Biophys. Res. Commun. 242 (2): 332–7. 1998. doi:10.1006/bbrc.1997.7877. PMID 9446795.
- "HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.". AIDS 12 (11): 1275–84. 1998. doi:10.1097/00002030-199811000-00008. PMID 9708406.
- "Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.". Eur. J. Immunol. 28 (10): 3183–91. 1998. doi:10.1002/(SICI)1521-4141(199810)28:10<3183::AID-IMMU3183>3.0.CO;2-A. PMID 9808187.
- "HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.". Blood 97 (2): 352–8. 2001. doi:10.1182/blood.V97.2.352. PMID 11154208.
- "HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.". FASEB J. 15 (2): 483–91. 2001. doi:10.1096/fj.00-0354com. PMID 11156964.
- "HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells.". J. Biol. Chem. 277 (28): 25195–202. 2002. doi:10.1074/jbc.M200921200. PMID 11994280.
- "Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.". J. Immunol. 169 (1): 254–60. 2002. doi:10.4049/jimmunol.169.1.254. PMID 12077252.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.". J. Virol. 77 (4): 2539–49. 2003. doi:10.1128/JVI.77.4.2539-2549.2003. PMID 12551992.
- "Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade.". J. Exp. Med. 198 (4): 653–9. 2003. doi:10.1084/jem.20030527. PMID 12925680.
- "Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells.". J. Neurovirol. 9 (6): 584–93. 2004. doi:10.1080/jnv.9.6.584.593. PMID 14602571.
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