Biology:PIK3R4
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Phosphoinositide 3-kinase regulatory subunit 4, also known as PI3-kinase regulatory subunit 4 or PI3-kinase p150 subunit or phosphoinositide 3-kinase adaptor protein, or VPS15 is an enzyme that in humans is encoded by the PIK3R4 gene.[1][2]
References
- ↑ "PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 [ Homo sapiens (human) "]. https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=30849.
- ↑ "Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex". J. Biol. Chem. 272 (4): 2477–85. January 1997. doi:10.1074/jbc.272.4.2477. PMID 8999962.
Further reading
- "Evidence That an Interaction between EB1 and p150Glued Is Required for the Formation and Maintenance of a Radial Microtubule Array Anchored at the Centrosome". Mol. Biol. Cell 13 (10): 3627–45. 2002. doi:10.1091/mbc.E02-01-0061. PMID 12388762.
- Koyasu S (2003). "The role of PI3K in immune cells". Nat. Immunol. 4 (4): 313–9. doi:10.1038/ni0403-313. PMID 12660731.
- "Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages". Nat. Cell Biol. 11 (4): 385–96. 2009. doi:10.1038/ncb1846. PMID 19270696.
- "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. 2004. doi:10.1101/gr.2435604. PMID 15342556.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. 2004. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9". Semin. Immunol. 16 (1): 17–22. 2004. doi:10.1016/j.smim.2003.10.009. PMID 14751759.
- "The Microtubule Plus-End Proteins EB1 and Dynactin Have Differential Effects on Microtubule Polymerization". Mol. Biol. Cell 14 (4): 1405–17. 2003. doi:10.1091/mbc.E02-03-0155. PMID 12686597.
- "hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells". Biochem. J. 417 (3): 747–55. 2009. doi:10.1042/BJ20081865. PMID 18957027.
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