Biology:PIK3R5
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 Generic protein structure example |
Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene.[1][2]
Interactions
PIK3R5 has been shown to interact with PIK3CG.[1]
References
- ↑ 1.0 1.1 "Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma". J Cell Biol 160 (1): 89–99. Jan 2003. doi:10.1083/jcb.200210115. PMID 12507995.
- ↑ "Entrez Gene: PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5, p101". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23533.
Further reading
- "Overexpression of p101 activates PI3Kgamma signaling in T cells and contributes to cell survival". Oncogene 26 (49): 7049–57. 2007. doi:10.1038/sj.onc.1210504. PMID 17486067.
- Rual JF; Venkatesan K; Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- Suire S; Coadwell J; Ferguson GJ et al. (2005). "p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma". Curr. Biol. 15 (6): 566–70. doi:10.1016/j.cub.2005.02.020. PMID 15797027.
- "Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma". J. Biol. Chem. 280 (6): 5121–7. 2005. doi:10.1074/jbc.M413104200. PMID 15611065.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus". J. Biol. Chem. 274 (39): 27943–7. 1999. doi:10.1074/jbc.274.39.27943. PMID 10488142.
- "Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits". J. Biol. Chem. 274 (24): 17152–8. 1999. doi:10.1074/jbc.274.24.17152. PMID 10358071.
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