Biology:PIP5K1A
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 Generic protein structure example |
Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha is an enzyme that in humans is encoded by the PIP5K1A gene.[1][2][3]
References
- ↑ "Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family". J Biol Chem 271 (51): 32937–43. Jan 1997. doi:10.1074/jbc.271.51.32937. PMID 8955136.
- ↑ "Assignment of type I phosphatidylinositol-4-phosphate 5-kinase (PIP5K1A) to human chromosome bands 1q22--> q24 by in situ hybridization". Cytogenet Cell Genet 88 (3–4): 197–9. Jun 2000. doi:10.1159/000015545. PMID 10828584.
- ↑ "Entrez Gene: PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8394.
Further reading
- "Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation.". Cell 99 (5): 521–32. 1999. doi:10.1016/S0092-8674(00)81540-8. PMID 10589680.
- "Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the golgi compartment.". J. Biol. Chem. 275 (18): 13962–6. 2000. doi:10.1074/jbc.C901019199. PMID 10747863.
- "Interaction of the type Ialpha PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4, 5-bisphosphate in the regulation of PLD2 activity.". EMBO J. 19 (20): 5440–9. 2000. doi:10.1093/emboj/19.20.5440. PMID 11032811.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932.
- "Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling.". J. Biol. Chem. 278 (25): 23036–45. 2003. doi:10.1074/jbc.M211397200. PMID 12682053.
- "Identification and characterization of a phosphoinositide phosphate kinase homolog.". J. Biol. Chem. 279 (12): 11672–9. 2004. doi:10.1074/jbc.M309721200. PMID 14701839.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha.". Mol. Cell. Biol. 25 (10): 3956–66. 2005. doi:10.1128/MCB.25.10.3956-3966.2005. PMID 15870270.
- "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. 2006. doi:10.1038/nature04727. PMID 16710414. Bibcode: 2006Natur.441..315G.
- "A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.". Curr. Biol. 16 (18): 1850–6. 2006. doi:10.1016/j.cub.2006.07.066. PMID 16979564.
- "Increasing plasma membrane phosphatidylinositol(4,5)bisphosphate biosynthesis increases phosphoinositide metabolism in Nicotiana tabacum.". Plant Cell 19 (5): 1603–16. 2007. doi:10.1105/tpc.107.051367. PMID 17496116.
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