Biology:PRKG1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
cGMP-dependent protein kinase 1, alpha isozyme is an enzyme that in humans is encoded by the PRKG1 gene.[1][2][3]
Interactions
PRKG1 has been shown to interact with:
References
- ↑ "Molecular cloning and predicted full-length amino acid sequence of the type I beta isozyme of cGMP-dependent protein kinase from human placenta. Tissue distribution and developmental changes in rat". FEBS Letters 255 (2): 321–9. Sep 1989. doi:10.1016/0014-5793(89)81114-7. PMID 2792381.
- ↑ "Localization of the human gene for the type I cyclic GMP-dependent protein kinase to chromosome 10". Cytogenetics and Cell Genetics 59 (4): 270–3. April 1992. doi:10.1159/000133267. PMID 1544322.
- ↑ "Entrez Gene: PRKG1 protein kinase, cGMP-dependent, type I". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5592.
- ↑ "cGMP-dependent protein kinase I beta physically and functionally interacts with the transcriptional regulator TFII-I". The Journal of Biological Chemistry 277 (35): 32003–14. Aug 2002. doi:10.1074/jbc.M112332200. PMID 12082086.
- ↑ 5.0 5.1 "Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta". Nature 404 (6774): 197–201. Mar 2000. doi:10.1038/35004606. PMID 10724174. Bibcode: 2000Natur.404..197S.
- ↑ "Molecular determinants of the interaction between the inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta". The Journal of Biological Chemistry 276 (26): 24153–9. Jun 2001. doi:10.1074/jbc.M101530200. PMID 11309393.
- ↑ "Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure". Nature Medicine 9 (12): 1506–12. Dec 2003. doi:10.1038/nm958. PMID 14608379.
- ↑ "A novel interaction of cGMP-dependent protein kinase I with troponin T". The Journal of Biological Chemistry 274 (52): 37429–34. Dec 1999. doi:10.1074/jbc.274.52.37429. PMID 10601315.
Further reading
- "Phosphorylation of the cystic fibrosis transmembrane conductance regulator". The Journal of Biological Chemistry 267 (18): 12742–52. Jun 1992. doi:10.1016/S0021-9258(18)42339-3. PMID 1377674.
- "Substrate- and kinase-directed regulation of phosphorylation of a cGMP-binding phosphodiesterase by cGMP". The Journal of Biological Chemistry 265 (25): 14971–8. Sep 1990. doi:10.1016/S0021-9258(18)77211-6. PMID 2168396.
- "Expression, purification, and characterization of the cGMP-dependent protein kinases I beta and II using the baculovirus system". FEBS Letters 374 (3): 419–25. Nov 1995. doi:10.1016/0014-5793(95)01168-E. PMID 7589584.
- "Phosphorylation of the inositol 1,4,5-trisphosphate receptor by cyclic GMP-dependent protein kinase". The Journal of Biological Chemistry 269 (12): 8701–7. Mar 1994. doi:10.1016/S0021-9258(17)37024-2. PMID 8132598.
- "cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets". The Journal of Biological Chemistry 269 (20): 14509–17. May 1994. doi:10.1016/S0021-9258(17)36652-8. PMID 8182057.
- "Phosphorylation of serine 2843 in ryanodine receptor-calcium release channel of skeletal muscle by cAMP-, cGMP- and CaM-dependent protein kinase". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1175 (2): 193–206. Jan 1993. doi:10.1016/0167-4889(93)90023-I. PMID 8380342.
- "cDNA cloning and gene expression of human type Ialpha cGMP-dependent protein kinase". Hypertension 27 (3 Pt 2): 552–7. Mar 1996. doi:10.1161/01.hyp.27.3.552. PMID 8613202.
- "Phosphorylation of purified bovine bone sialoprotein and osteopontin by protein kinases". The Journal of Biological Chemistry 271 (28): 16897–905. Jul 1996. doi:10.1074/jbc.271.28.16897. PMID 8663267.
- "Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase". Science 273 (5277): 959–63. Aug 1996. doi:10.1126/science.273.5277.959. PMID 8688081. Bibcode: 1996Sci...273..959X.
- "Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1)". Genomics 42 (2): 311–8. Jun 1997. doi:10.1006/geno.1997.4743. PMID 9192852.
- "Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB". The EMBO Journal 17 (15): 4426–41. Aug 1998. doi:10.1093/emboj/17.15.4426. PMID 9687510.
- "CREB is a regulatory target for the protein kinase Akt/PKB". The Journal of Biological Chemistry 273 (49): 32377–9. Dec 1998. doi:10.1074/jbc.273.49.32377. PMID 9829964.
- "Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells". Proceedings of the National Academy of Sciences of the United States of America 96 (5): 2467–72. Mar 1999. doi:10.1073/pnas.96.5.2467. PMID 10051666. Bibcode: 1999PNAS...96.2467E.
- "Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly". The EMBO Journal 18 (16): 4549–59. Aug 1999. doi:10.1093/emboj/18.16.4549. PMID 10449420.
- "Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase Ialpha". Science 286 (5444): 1583–7. Nov 1999. doi:10.1126/science.286.5444.1583. PMID 10567269.
- "A novel interaction of cGMP-dependent protein kinase I with troponin T". The Journal of Biological Chemistry 274 (52): 37429–34. Dec 1999. doi:10.1074/jbc.274.52.37429. PMID 10601315.
- "Binding and phosphorylation of a novel male germ cell-specific cGMP-dependent protein kinase-anchoring protein by cGMP-dependent protein kinase Ialpha". The Journal of Biological Chemistry 275 (7): 4897–905. Feb 2000. doi:10.1074/jbc.275.7.4897. PMID 10671526.
- "Cysteine-rich protein 2, a novel substrate for cGMP kinase I in enteric neurons and intestinal smooth muscle". The Journal of Biological Chemistry 275 (8): 5504–11. Feb 2000. doi:10.1074/jbc.275.8.5504. PMID 10681529.
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