Biology:PRKY
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Short description: Pseudogene in the species Homo sapiens
Generic protein structure example |
Serine/threonine-protein kinase PRKY is an enzyme that in humans is encoded by the PRKY gene.[1][2]
This gene encodes a member of the cAMP-dependent serine/threonine protein kinase family. This gene is located on chromosome Y, near the boundary of the pseudoautosomal region. Abnormal recombination between this gene and a related gene on chromosome X is a frequent cause of XX males and XY females.[2]
References
- ↑ "The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability". Hum Mol Genet 4 (5): 869–78. Sep 1995. doi:10.1093/hmg/4.5.869. PMID 7633447.
- ↑ 2.0 2.1 "Entrez Gene: PRKY protein kinase, Y-linked". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5616.
Further reading
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes". Nature 423 (6942): 825–37. 2003. doi:10.1038/nature01722. PMID 12815422. Bibcode: 2003Natur.423..825S.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "A selective difference between human Y-chromosomal DNA haplotypes". Curr. Biol. 8 (25): 1391–4. 1999. doi:10.1016/S0960-9822(98)00020-7. PMID 9889101.
- "Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females". Hum. Mol. Genet. 6 (11): 1985–9. 1998. doi:10.1093/hmg/6.11.1985. PMID 9302280.
- "FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12→q13". Cytogenet. Cell Genet. 76 (1–2): 49–52. 1997. doi:10.1159/000134514. PMID 9154127.
- "High-resolution fluorescence in situ hybridization of human Y-linked genes on released chromatin". Chromosome Res. 5 (1): 23–30. 1997. doi:10.1023/A:1018437301461. PMID 9088640.
Original source: https://en.wikipedia.org/wiki/PRKY.
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